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In the early 21st century, the Danish company Novo Nordisk successfully developed Liraglutide, a peptide drug with 97% homology to human GLP-1
These transdermal products face similar evidence limitations as oral supplements, with the added concern that berberine delivery through the skin has not been well studied
It's a short-term solution, usually prescribed for a few weeks, for people who are significantly overweight and have failed to achieve desired results with diet and exercise alone
This work was supported by a grant (01GI0925) from the Federal Ministry of Education and Research (BMBF) to the German Center for Diabetes Research
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