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Plus, they were developed to treat diabetes, so we have less clarity about how safe they are for people without that disease
This new class of medication proved to be so effective, it was fast-tracked for FDA-approval as a weight loss medication
Seek urgent medical advice if you experience: Severe or recurrent hypoglycaemia (blood sugar below 4 mmol/L) Symptoms of hypoglycaemia that do not improve with treatment Severe, persistent abdominal pain, especially if radiating to the back (this could indicate pancreatitis, a rare but serious side effect of GLP-1 receptor agonists) [2] Persistent or severe gastrointestinal symptoms such as vomiting, severe diarrhoea, or abdominal pain Signs of dehydration (dry mouth, reduced urination, dizziness) Any new or worsening symptoms after starting berberine If you cannot reach your GP and need urgent advice, contact NHS 111
Practical Summary In short, GLP-1 medications like compounded semaglutide and tirzepatide are excellent for shedding fat by curbing hunger and boosting metabolism, while Sermorelin helps keep muscles strong and bones solid through higher IGF-1 levels
