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Hershman of Columbia University in New York, so this is not like a lot of studies where you find a statistically significant difference thats not clinically meaningful. In addition, the incidence of grade 3/4 neurotoxicity was 3.8% with ALC, much higher than the 0.5% seen with placebo
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As much as possible, when lightening effect is already observed, one may shift to oral glutathione which is safer
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