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Estimates for humans, based upon fraction of drug excreted in urine and assuming mostly hepatic metabolism, suggest a higher threshold of 400-500 daltons for favorable biliary vs renal excretion of small organic molecules
Rotate sites systematically (abdomen preferred
Xu Wang, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
It operates on the whole body, not just one part
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