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Lee DM, Kim IY, Lee HJ, et al

Yet, low-dose riboflavin supplements may potentially reduce blood pressure and lower the risk of heart disease in people who are genetically predisposed to them

While large-scale randomized trials in MCAS are limited, case-report literature describes improvement in patients with overlapping conditions such as MCAS and severe postural orthostatic tachycardia syndrome (POTS) when naltrexone was included as part of a comprehensive care plan

271 Furthermore, a STING mutant unable to bind Ca 2+ failed to trigger an IFN response under conditions of pathogenic stimuli insufficiency, highlighting the essential role of Ca 2+ binding in STINGs function