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A 2026 systematic review and meta-analysis of controlled human trials found that allulose (and its cousin tagatose) meaningfully reduced the postprandial glucose response when used in place of added sugars, an effect that may be especially useful in the window right after a carbohydrate-rich meal
Consistent use over several weeks or even months is often needed to see significant changes
This smaller size generally allows them to be very readily absorbed and used by the body, said Mehrotra
However, some people cannot take vitamin B12 injections safely, including those with Lebers disease or similar eye concerns, kidney disease, liver disease, iron or folic acid deficiency, an active infection, or those taking medications that may interact with vitamin B12
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