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Biol Med
This model prioritizes accessibility while maintaining the clinical efficacy documented in major weight loss trials
Some reasons patients consider deprescription include: Negative side effects Cost and coverage challenges Difficulty adhering to treatment Reaching their health goals Hitting a weight-loss plateau Preference not to remain on medication long term Without a comprehensive lifestyle and nutrition plan, many patients who stop GLP-1s regain the weight they lost
Half-life ~30 min plasma half-life reported in rat models (subcutaneous administration)
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