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If no adverse effects occur, increase to 300-500mcg for the remainder of the cycle
Probably, especially for higher-risk groups
Both semaglutide and tirzepatide may be considered for non-diabetic patients when clinically appropriate
AI and AI-assisted tools statement During the preparation of this manuscript, the AI tool ChatGPT (GPT-5, released 2025-08-07) was used to generate Figure 1 and the Graphical Abstract and to improve the readability and language of the manuscript
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