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Once this interaction is disrupted: p53 is released from the nucleus Cellular self-destruction pathways are activated Senescent cells undergo apoptosis This selective mechanism has made FOXO4-DRI one of the most studied senolytic peptides in modern aging research

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To study maturation rates and oocyte quality parameters, 980 cumulusoocyte complexes (COCs) were matured in vitro and further examined

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