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Frontiers in Endocrinology, 17

Key evidence-based strategies include: Calorie-controlled diets tailored to individual needs, with a focus on whole foods, vegetables, lean proteins, and reduced ultra-processed food intake Regular physical activity the NHS recommends at least 150 minutes of moderate-intensity exercise per week for adults, alongside strength training on two or more days [15] Behavioural interventions , including cognitive behavioural therapy (CBT) approaches, which address eating habits and psychological relationships with food NHS weight management programmes , such as referral to Tier 2 or Tier 3 services depending on BMI and comorbidities

Clinical studies have shown tirzepatide to produce greater average weight loss and glycemic improvement than semaglutide in comparable populations

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