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Both TB-500 and BPC-157 have demonstrated a favorable safety profile in preclinical studies and limited clinical trials

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Dina Peralta-Reich, MD, FAAP, FOMA, and Director of New York Weight Wellness Medicine said that the gastrointestinal side effects of these medications, like nausea and vomiting, may be worse in older people, which may set them up for dehydration, weakness, or nutritional deficiencies. Monitoring water intake can be challenging, and it is crucial to avoid dehydration, which may result in dizziness, falls, fainting, and possibly fractures, she said

Voluma is a very stiff, bouncy, lifting filler and that could create problems in 2 ways: Voluma could become visible through the thinner-than-usual skin under the eyes, creating weird lumps and bumps (this is why Voluma is injected deep into tissues of the face and never superficially) Voluma creates lift in the areas where its injected - and too much lift under the eyes could create a puffy, unnatural look Now, sometimes you will see the undereye of a patient improve after having had Voluma injected, but that Voluma is injected into the cheeks