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Fat loss diets may also contribute to an increase in toxic burden due to the release of toxins stored in fat cells, and this may be a reason why supporting detoxification during fat loss is a wise decision

Table 9.232 Tissue gamma-tocopherol and alpha-tocopherol concentrations (nM/g)1 Reference Wagner KH, Kamal-Eldin A, Elmadfa I

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Methionine's half-life in plasma is approximately 2.5 hours, but its functional duration as a methyl donor extends 4872 hours because SAMe persists in hepatocytes after the parent amino acid clears circulation