tirzepatide weight loss surmount-1 results percent weight loss 72 weeks Dose-equivalence reference based on pivotal GLP-1/dual-agonist trials: (tirzepatide/Zepbound, weeks) STEP-1 (subcutaneous semaglutide/Wegovy, 68 weeks) OASIS-4 (oral semaglutide/Wegovy, 64 weeks). For educational comparison only—these are SURMOUNT‐1 study design. This is
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