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According to the Wegovy Summary of Product Characteristics (SmPC), treatment should be discontinued if a patient has not lost at least 5% of their initial body weight after 12 weeks on the maintenance dose (2.4 mg once weekly)
Once reconstituted, store the vial under refrigeration at 28C and use within the peptides documented stability window
Because these medications often reduce food intake, it becomes easier to fall short on key nutrients
These data suggest a combination effect of GPR17 constitutive and agonist-mediated inhibition of GPBAR-A-stimulated GLP-1 secretion
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