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It would be great to undertake studies with the newer dual agonists and polyagonists also in rare obesity syndromes such as AS, Prader-Willi syndrome, and Bardet-Biedl syndrome (just to name a few) as the clinical need for effective obesity/hyperphagia therapies in these patients is especially high, says Scherer

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Drug Development and Approval Process. This article provides educational information based on clinical trial data and should not replace personalized medical advice

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Future options like orforglipron (non-peptide, expected 2026) may simplify timing

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