I recommend more caution if If you have a family history of any oxidative stress induced neurodegenerative or neurodevelopmental issues (Parkinsons, autism, tics, etc), this is a possible indicator of genetic predisposition to poor detoxification
(2023) Retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in type 2 diabetes The New England Journal of Medicine 389(6):503-513
A new sustained-release microsphere formulation of exenatide, known as DA-3091, has shown promise in managing obesity, diabetes, and nonalcoholic fatty liver disease, offering effective metabolic control with less frequent dosing, potentially improving patient compliance
Vomiting becomes more common at this stage, particularly if large meals, rich foods, or alcohol are consumed