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However, this hypothesis lacks supporting evidence

For clients with more complex hormonal or digestive concerns, we may also recommend a DUTCH Test to get a fuller picture of what is driving gut dysfunction

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The Biochemical Relationship (Simplified) NAD+ metabolism produces NADPH NADPH is required to keep glutathione in its active (reduced) form Active glutathione neutralizes oxidative stress Reduced oxidative stress helps preserve NAD+ levels In other words: NAD+ helps keep glutathione working