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Using gene-edited mice with humanised GLP-1 receptors, the team found that oral small-molecule GLP-1 drugs activated the central amygdala, a region associated with desire and reward that sits deeper in the brain than the hypothalamic and hindbrain networks where injectable peptide GLP-1s have been shown to act
The GLP-1 medication is truly life-changing
The convenience of pre-mixed liquid comes with a trade-off
This gentler approach prevents foaming and protein damage
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