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GLP-1 medications, such as semaglutide and liraglutide, mimic this hormone to help regulate blood sugar levels, promote insulin secretion, and inhibit glucagon release

These agents act through multiple mechanisms, including direct cardioprotection, vasodilation, natriuresis, weight reduction, lipid profile improvement, anti-inflammatory effects, renal protection, reduction in plaque formation, and neurohormonal regulation

Separate linear mixed effects models were used to test for changes in baseline A1C and BMI over time, using a random effect to account for variation in level by drug

The first month is dose-finding, not rapid loss