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[5] Importantly, if both B12 and folate deficiencies are present, B12 should be corrected first to avoid potentially worsening neurological symptoms

Dose-response relationships in healthy young and middle-aged adults

However, there are certain health conditions and circumstances that may be negatively affected by the injections, including: Pregnancy Breastfeeding Cancer Advanced liver disease Seriously compromised kidney function Hypotension 4 Your Provider Injects Vitamin B12 Shots Intramuscularly This means the solution gets injected directly into your muscles

Prolonged use of Vitamin B6 (over 2 months) at high doses exceeding 1g/day can lead to severe peripheral neuropathy, with symptoms including unsteady gait and numbness in the hands and feet