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To improve the BBB permeability of cytotoxic T-lymphocyte associated antigen 4 (a-CTLA-4) and programmed cell death-1 (a-PD-1) for immunotherapy of brain glioma, Ljubimova and co-workers described a nanoscale immunoconjugate system

The one significant finding came from a patient questionnaire: self-reported improvement in overall skin quality favoured the GHK-Cu group (P = 0.04).[6] Other frequently quoted claims include increased skin thickness, improved elasticity and reduced wrinkles are largely derived from older cosmetic studies and company-linked research

2018;172(3):409422.e21

Graphical abstract Similar content being viewed by others Introduction Chronic infections, characterized by persistent inflammation and microbial colonization that fail to resolve within expected timeframes, represent a serious and debilitating Health challenge