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In diabetes, diminished abundance of Akkermansia , Bacteroides , Bifidobacterium , Faecalibacterium , and Roseburia reduces -glucuronidase and 7-dehydroxylase activities, thereby blocking the conversion of primary BAs to secondary BAs and consequently decreasing the synthesis of DCA and LCA (Li et al., 2021b)
Patients with diabetes should monitor blood glucose carefully, as alcohol can increase hypoglycaemia risk, particularly when combined with insulin or sulfonylureas
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