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Compared to the previously standard Escherichia coli BirA, its kinetic rate was increased by over 1000-fold, and the signal-to-noise ratio was improved by over 30-fold

Isolated riboflavin deficiency is rare and typically associated with risk factors including the acute or chronic consumption of alcohol, the use of birth control pills, and the administration of antimalarial agents and antidepressants, which can impair absorption (5, 44, 45)

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