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Moreover, although the autophagy of mitochondria (mitophagy) may sequester iron in mitophagosomes to prevent iron from releasing into the cytoplasm in the early stages of iron overload, extensive mitophagy can conversely trigger Fe 2+ liberation, elevate cytosolic Fe 2+ levels, and amplify ferroptosis (Yu et al., 2022

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Two makers of GLP-1s, Eli Lilly and Novo Nordisk, established direct-to-consumer programs to allow patients to buy the medicines without using insurance at prices as low as $149 for starter doses and between $250 and $375 for monthly maintenance doses

PLoS ONE 8, e56711, 10.1371/journal.pone.0056711 (2013)