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Cytochrome P450 4F2 (CYP4F2) initiates -oxidation of tocochromanols, a process that is followed by -oxidation to carboxyethyl hydroxychromanol (CEHC), which can be conjugated with glucuronide or sulfate and excreted in urine or bile
It highlights the bidirectional interactions between redox imbalance, mitochondrial function, and circadian clock regulation, with particular attention to the antioxidant role of melatonin
Anti-aging and cellular damage repair slows down free radical damage and protects brain function
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