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Glucuronidation also contributes to ochratoxin A detoxification, so UGT variants may have an overlapping impact across several mycotoxins.[ref] Related article: Glucuronidation: UGT Genetic Variants, Detoxification, and Hormone Balance Patulin and glutathione-dependent pathways: Patulin, a mycotoxin most commonly found in moldy apples and apple juice, binds to thiol groups in glutathione, depleting this key intracellular antioxidant and triggering oxidative stress and mitochondrial dysfunction
Briefly, cells were fixed, processed, mounted on Epon stubs, polymerized at 60 C, and 70 nm sections cut en face with a diamond knife (DiATOME) in a Leica Ultracut UCT ultramicrotome before examination on an FEI Tecnai G2-Spirit TEM
Direct answer: Weight regain is common if lifestyle habits do not fully support long-term maintenance
