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Opened but unreconstituted vials should be used within one to three months rather than the year-plus timeframe of sealed vials
The rationale is borrowed from other compounds where tissue saturation and receptor dynamics justify phased dosing
For properly screened individuals, high-dose IV vitamin C has an excellent safety profile
The kidneys receive approximately 25% of cardiac output, so the major driving force for glomerular filtration is the hydrostatic pressure within the glomerular capillaries
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