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Melatonin occurs in mitochondria in higher abundance compared to blood
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Be on the lookout for serious symptoms , including redness that spreads beyond 2 inches, increasing swelling, intense pain, fever, chills, or trouble breathing
Consistent with this, use of a reducing source such as -mercaptoethanol allows reversal of xCT-KO phenotype, as it has been reported couple decades ago by Bannai's group ( in vivo can explain the discrepancy with in vitro phenotype
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