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This work was partly supported by Grants-in-Aid from the Japan Society for the Promotion of Society (17K16958 to K.S., 17H04349 to T.N.)
For instance, in the STEP 2 trial, nausea from semaglutide rose from 5% at week 1 to 15% by week 13, then decreased to 8% by week 68
Prescribing information for approved GLP-1 medications does not list colorectal cancer as a known adverse effect, though the FDA requires ongoing post-marketing surveillance for all novel therapeutic agents
Always consult with a healthcare provider before starting any new medication or treatment
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