More impressively, up to 83% of those on the highest dose lost at least 15% of their weight , compared to only 2% of placebo patients
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To determine which genes drive the differences in transcriptional landscape among the various subclusters, we focused on functionally related genes that exhibited high differential expression between each subcluster within individual endocrine cell populations as well as other known and cell marker genes
Drug Metab Dispos 38:16651672 Kato Y, Kubo Y, Iwata D, Kato S, Sudo T, Sugiura T, Kagaya T, Wakayama T, Hirayama A, Sugimoto M, Sugihara K, Kaneko S, Soga T, Asano M, Tomita M, Matsui T, Wada M, Tsuji A (2010) Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1