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Total proteomics in SK-MEL-103 cells undergoing senescence and treated with SCLA2/2a/2b SK-MEL-103 cells grown in six-well plates were treated with either etoposide or tozasertib to induce senescence or DMSO as a control for 6 days (Supplementary Table 8)

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Tirzepatide (GLP-1/GIP agonist): In pharmacovigilance analyses, semaglutide showed a stronger signal for depression reports, whereas tirzepatide did not despite tirzepatides potent metabolic effects (eClinicalMedicine 2025)