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Subsequent biochemical and cytochemical studies demonstrated that HGF nitration is maximal in a physiological pH range at Y198 and Y250, characterized by their respective locations at the c-met binding sites of the K1 and K2 domains of the HGF -chain
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Across the Phase 2 trials, participants experienced an average systolic blood pressure decrease of 6.8 mmHg
Patients with tight anal sphincter muscles (i.e., increased muscle tone) are more prone to developing anal fissures
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