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Published: Thursday, December 11, 2025 OKLAHOMA CITY The success of GLP-1 medications for treating Type 2 diabetes and obesity naturally leads to a related question: Do GLP-1 drugs affect cancer risk, which is often associated with obesity and Type 2 diabetes
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At 1 mg its occupancy sits near 1%, and liver fat still fell 51% over 48 weeks in the trial participants who started with fatty liver. Natural glucagon reaches a similar 0.5 to 5% engagement during a fast, so 1% is not an unusually small signal
They have a similar structure to the hormone glucagon-like peptide 1 (GLP-1), which means taking these medications tricks your body into thinking GLP-1 levels are high
