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DSIP also modulates the hypothalamicpituitaryadrenal (HPA) axis, lowering nighttime cortisol spikes and reducing stressrelated arousal, which contributes to more stable circadian rhythms Peptide therapy for sleep has an excellent safety profile when administered under qualified medical supervision, with minimal side effects and no dependency risk

Tirzepatide, a dual GLP-1 and GIP receptor agonist, has been newly approved by the FDA for managing moderate to severe OSA, following promising results from major randomized trials

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