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Neutralizing antibodies to tesamorelin and hGHRH were detected in vitro at Week 52 in 10% and 5% of tesamorelin-treated patients, respectively
In contrast to M1 macrophages, M2 macrophages secrete anti-inflammatory factors such as IL-10 and TGF- to inhibit the production of inflammatory mediators and MMPs, and they can also clear free hemoglobin and regulate oxidative stress, which will promote vascular remodeling and repair (288, 293)
These features greatly limit GSH accumulation
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