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Once primarily a concern for high-income countries, excess weight and obesity is now widespread across many different regions, income levels and age groups, making it one of the worlds biggest public health concerns

As the inflammation settles, the midsection continues to take shape, and the final results become more noticeable over the following months

Early data also suggest potential benefits in liver disease, obstructive sleep apnea, chronic respiratory disorders, neurodegenerative and psychiatric conditions, reproductive dysfunction, obesity-associated cancers, and sepsis, although these remain investigational

Optimal metabolic function requires both sufficient hormone production and robust receptor-mediated signaling