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Biochem Soc Trans 36:976980 Andreyev AY, Kushnareva YE, Starkov AA (2005) Mitochondrial metabolism of reactive oxygen species
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Properties: The drug is a combination of two hypoglycemic drugs with a complementary mechanism of action, designed to improve glycemic control in patients with type 2 diabetes mellitus: sitagliptin, an inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), and metformin, a representative of the biguanide class
Its impact on hormones and liver health demonstrates it can be used to address issues such as non-alcoholic fatty liver disease, insulin resistance, and metabolic syndrome
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