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Undesirable effects: Very Common (10%): nausea, vomiting, diarrhoea, constipation, abdominal pain, headache, fatigue
Timing, dosing, and administration decisions should be made in consultation with a qualified research supervisor or licensed prescribing physician where applicable
Decreased appetite is also very common and may contribute to the weight reduction observed in some patients
A post hoc analysis of the phase IIb trial showed that tirzepatide was associated with a reduction in the level of high-sensitivity ICAM-1, CRP, and YKL-40 after 26 weeks of treatment in a dose-dependent manner [83, 103]
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