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Risk ratios (RR) for nonfatal stroke estimates according to direct (DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors against placebo) and indirect (DPP-4 inhibitors vs GLP-1RA or SGLT-2 inhibitors, and GLP-1RA vs SGLT-2 inhibitors) comparisons
Best in combination Benefit is more meaningful when diet, undermethylation, histamine, zinc and toxic burden are addressed simultaneously
GI strategies: smaller, more frequent meals
Few in vitro trials have explored this issue, 151 but no additional data are available to clarify it
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