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While Rybelsus (semaglutide) is primarily metabolised via proteolytic cleavage rather than through the cytochrome P450 system, berberine's effects on drug-metabolising enzymes and transporters could theoretically influence other medications you may be taking
But you need to know the difference between normal titration effects and signs that something more serious is happening
Contraindications GLP-1s arent recommended for those with a history of thyroid carcinoma, pancreatitis, some endocrine conditions, and GI motility disorders
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