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This deeper, more targeted approach makes ultrasound technologies a strong option for areas such as the brow, neck, double-chin (or submental area) or jawline, locations where GLP-1related fat loss may make lines or folds more visible

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Although direct clinical evidence of systemic NAD(P) depletion during GLP-1RA therapy is lacking, experimental and observational studies suggest that NAD turnover and micronutrient status can be altered in obesity and inflammatory states [83, 85], supporting the biological plausibility of substrate-sensitive vulnerability