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Lillys oral GLP-1 candidate, orforglipron, delivered a 12.4% average body weight reduction in a Phase 3 trial over 72 weeks
These options are prescribed only when appropriate and based on individual patient needs
Older medications like phentermine temporarily increase alertness and heart rate but don't address underlying metabolic dysfunction or preserve muscle mass
For example, semaglutide should be stopped at least 2 months before a planned pregnancy according to manufacturer's guidance, and you should discuss this timing with your GP or diabetes specialist
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