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In a zebrafish model, compared with C3-carnitine, C18-carnitine and C18:1-carnitine can induce the inhibition of OXPHOS, interfere with the energy supply of cardiomyocytes, and lead to a significant impairment of cardiac systolic function, which manifests as a decreased heart rate and reduced shortening of the atrial and ventricular fractions [21]
cureus [Internet]
The heterogeneity of these experiences underscores the complexity of attributing cognitive changes directly to GLP-1 receptor agonism versus the multiple physiological changes these medications induce
Psychiatry 10 (1), 238
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