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Although encouraging, the results of this study should be interpreted in the context of several key limitations, the researchers said
Altering the tablet in any way may affect how it works and could lead to reduced effectiveness or unpredictable absorption
Moreover, the actions of semaglutide to reduce body weight, improve glucose tolerance, and decrease circulating levels of triglyceride-enriched lipoproteins were not diminished in Glp1r Tie2/ mice, revealing that GLP-1Rs within the Tie2 expression domain, including IEL GLP-1R, are not required for these metabolic actions of semaglutide
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 18(10), 22262233.e4
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