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Clinical studies have confirmed that hyperhomocysteinemia is not only an independent risk factor for the development of cardiovascular and cerebrovascular diseases, such as atherosclerosis, acute myocardial infarction, stroke, coronary artery lesions, and peripheral vascular disease, but also increases the risk of neurodegenerative disorders and tumors, and impairs the efficacy of antifolate drugs
For example, an 8-week study of 38 women found no difference between those who took L-carnitine and those who didnt when combined with equal exercise for both groups
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