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Significance is indicated with asterisks * and a minimum P value of 0.05 was considered statistically significant (refer to figure legends for details)

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Additionally, collagen-based supplements with short lengths and low molecular weights are more effective, as they can efficiently embed into the active sites of ACE to impair its activity (Fig

A concrete example that clarifies this boundary is gastrin: multiple adequately powered human trials demonstrated that gastrin-based therapies failed to preserve beta-cell function in type 2 diabetes, and development was largely discontinued by approximately 2010