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Because GH levels naturally decline with age, this decline is closely associated with increased visceral fat accumulation around the midsection
![how long to lose 20 lbs on semaglutide vs Tirzepatide for Weight Loss M/32/5'8 [195lbs > 175lbs =20lbs]](https://preview.redd.it/m-32-58-195lbs-175lbs-20lbs-6-months-semaglutide-weight-v0-bqkcss0qud5f1.jpeg?width=640&crop=smart&auto=webp&s=a858bd8fcb036131142ea0d126985db0af8b2aed)
The SURPASS-CVOT trial is underway but results have not been published
![how long to lose 20 lbs on semaglutide vs Tirzepatide for Weight Loss M/32/5'8 [195lbs > 175lbs =20lbs]](https://i.ytimg.com/vi/GiwpOSU0HTU/hq720.jpg?sqp=-oaymwEhCK4FEIIDSFryq4qpAxMIARUAAAAAGAElAADIQj0AgKJD&rs=AOn4CLBbm1I3CNPMTAOZuvciqXMoug-Mdw)
Cognitive-behavioral therapy, mindfulness practices, and, when appropriate, psychiatric medication can address these contributors to brain fog
![how long to lose 20 lbs on semaglutide vs Tirzepatide for Weight Loss M/32/5'8 [195lbs > 175lbs =20lbs]](https://floridaweightlossmd.com/wp-content/uploads/2026/02/GLP-1-Tirzepatide-How-Long-to-Lose-10%E2%80%9370-Pounds-1024x690.jpg)
By maintaining estrogen levels through HRT while losing weight with GLP-1 medications, you may protect bone density better than with GLP-1 medications alone
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