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doi: 10.2147/DDDT.S327378 230 SunHLiuTWangZShenWYuanXXieJet al
The research on natural inhibitors from land and sea is mostly limited to the preliminary screening of known compounds, and their structure-activity relationship and mechanism of action have not been fully clarified - especially the targeting optimization of marine resources (only a small part of which have been verified) and human-specific tyrosinase (which has structural differences with mushroom sources) needs to be broken through
Additionally, the specificity of these results to the NNMTi 5A-1MQ and the dosage used herein also require further evaluation
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