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Conversely, GSH depletion in cancer cells reduces SSG, leading to oxidative stress and autophagy activation (46)
Reduced cAMP and inactive PKA result in increased Ca 2+ mobilization inside the platelet, facilitating activation and aggregation
Ao contrrio do que se poderia pensar, mais nem sempre melhor: os peptdeos atuam por sinalizao e no por saturao, pelo que concentraes moderadas e bem formuladas podem ser to eficazes quanto ou mais estveis do que concentraes muito altas
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