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No More Is Always Better Mentality: While B12 is generally safe, taking excessive amounts when not needed simply means your body will excrete the excess, making it a waste of money and potentially masking underlying issues if youre self-treating
For these patients, oral B12 supplementation (1,000-2,000 mcg daily sublingual methylcobalamin) provides comparable B12 repletion without injection
When mitochondrial damage occurs, PINK1 accumulates on the mitochondrial outer membrane and recruits the E3 ubiquitin ligase Parkin (Picca et al., 2023)
Furthermore, this substance is not approved for human clinical use by any global regulatory authority and it may lead to negative health effects
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